These doses are approximately 5.5 and 33 times, respectively, the maximum recommended human dose (MRHD) of 70 mg/day given to adults, on a mg/m2 body surface area basis
Those two individuals were notably taking multiple peptides at once
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Other obvious limitations of this Polish study (132) are the lack of details on the degree of hypothyroidism (overt, subclinical, either), the magnitude of change in serum levels of TSH, and having neglected to obtain information on changes in serum thyroid autoantibodies
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