Eder L, Chandran V, Gladman DD
Noppe G, Dufeys C, Buchlin P, Marquet N, Castanares-Zapatero D, Balteau M, Hermida N, Bouzin C, Esfahani H, Viollet B, Bertrand L, Balligand JL, Vanoverschelde JL, Beauloye C, Horman S (2014) Reduced scar maturation and contractility lead to exaggerated left ventricular dilation after myocardial infarction in mice lacking AMPKalpha1
The latter is also supported by the TODINELI-trial (Brock et al., 2019), where treatment of type 1 diabetic patients with liraglutide reduced levels of proinflammatory cytokines (IL-6) but did not improve the status of patients that had already established autonomic or diabetic polyneuropathy
Clin Translational Immunol
Brain Dev 34:5763
By enhancing Treg function, LDN provides powerful immune modulation , calming the autoimmune assault on the thyroid gland