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This also represents the contrast between investigator initiated and governmental agency funded trials (TOPCAT, SPIREN, BARACK-D) in which the eligibility/enrolment were messed up or not achieved, interventions were completely missed or dropped out early, and possibly many other gaps and slips

The combination appears to produce effects greater than the simple sum of individual contributionsa phenomenon researchers term synergistic efficacy

The injection must always be given by a trained healthcare professional

(2015) 38:e134