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Compounded semaglutide, on the other hand, is not exactly the same

Below is a chart on mechanisms of action and why the additional GIP activity of Tirzepatide makes it more efficacious than Semaglutide

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[1] However, the combination may present practical considerations rather than pharmacological contraindications

Menon KV, Stadheim L, Kamath PS, Wiesner RH, Gores GJ, Peine CJ, et al