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No official human safety or efficacy data

A fifty-year-old man with low-normal testosterone could experience improved free testosterone, better body composition, and restored sexual function

The aim is not to dismiss patient interest in new therapies

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However, as explained by the Alzheimers Drug Discovery Foundation in 2024, while urolithin A does have an impressive safety profile, its long-term safety has yet to be established.4 Also, while rare, some people can be allergic to pomegranates, which are rich in the polyphenols that are metabolized into urolithin A.21 This doesnt necessarily mean that those with pomegranate allergies will have a reaction to urolithin A supplements, but it could be something to keep in mind

The world of biochemistry is a complex one, and understanding the various aspects of it can be difficult