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GHRH (0.3 micrograms/kg body wt) was given in early sleep [i.e., 1st slow-wave (SW) period], late sleep (i.e., 3rd REM period), and early sleep after sleep deprivation until 0400 h (i.e., 1st SW period)

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Lysosomal hydrolases are synthesized in the endoplasmic reticulum (ER), modified in the Golgi apparatus with mannose 6-phosphate tags, and recognized by mannose 6-P receptor (MPR)

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