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Qualified manufacturers follow their applicable standards of practice, which are less stringent than those for FDA-registered drug manufacturers

The principal incretins are the glucose-dependent insulinotropic polypeptide (GIP) and the glucagon-like peptide-1 (GLP-1), representing the endogenous physiological substrates for DPP4 activity [34, 35]

Compounded drugs are not FDA-approved, officials said, which means they have not been vetted for safety in humans

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Some may eventually become useful medicines

8% of the plaintiffs allege other serious gastrointestinal complications, such as extreme vomiting, chronic acid reflux or abdominal pain that required multiple hospitalizations in some cases