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Obesity is a long-term, or chronic, disease

This finding highlights a fundamental distinction that must be applied when interpreting the preclinical literature as a whole: the majority of studies reporting positive outcomes employed a preventive or co-treatment paradigm, in which the drug was administered prior to or concurrently with pathological induction

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Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors

However, their precise mechanisms of action remain under investigation