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For example: Fatigue, unexplained weight loss, or abdominal pain may indicate liver disease or cancer Easy bruising, night sweats, or feeling full quickly (early satiety) may suggest a myeloproliferative disorder Swelling in the legs, reduced urine output, or persistent nausea may point to kidney disease In cases of very high B12 from injections (not oral supplements), some people have reported headache, nausea, diarrhea, facial flushing, or skin rash

Real-world stories A patient I followed for years believed monthly B12 shots were the secret to her energy despite normal labs

[2] [3] [4] Alcohol may also cause death indirectly by asphyxiation, caused from vomiting

Injections of compounds involved in hepatic fat metabolism classically methionine, inositol and choline, often with vitamin B12

Megadoses of B12 can lead to headaches, nausea, diarrhea, vomiting, and flushing, he says

The results have been wild