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doi: 10.3389/fonc.2025.1568391 Received 06 February 2025 Accepted 23 May 2025 Published 09 June 2025 Corrected 17 July 2025 Volume 15 - 2025 Edited by Jianqiang Xu, Dalian University of Technology, China Reviewed by Sivapar V

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The 48-hour minimum spacing ensures that: 1