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Abstract Background Incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), play an important role in meal-related insulin secretion

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Additionally, GLP-1RAs exhibit pleiotropic effects on metabolic and cardiovascular pathways, which could influence arrhythmia risk through mechanisms such as glucose homeostasis, blood pressure regulation, and autonomic modulation

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The siblings without Down syndrome had higher concentrations of GSH (reduced form), GSSG (oxidised form) and total GSH, but the difference was not statistically significant

They cannot use nutrients until they have been broken down into their inorganic form