PE035005: NeuAcα(2-6)LacNAc-PEG3-Thiol label-new / MUC1(137-141)-Tn(139) / Mucin1

/ MUC1(137-141)-Tn(139) / Mucin1

2-[2-(2-Aminoethoxy)ethoxy]ethyl β-D-galactopyranoside

4-MU-a-IdoA 2-sulfate

This compound presents the core 1 O-glycan / T antigen (Galβ1-3GalNAcα) on a threonine residue

isosteric with the native hydroxyl

PE035005: NeuAcα(2-6)LacNAc-PEG3-Thiol label-new / MUC1(137-141)-Tn(139) / Mucin1C31H54N2O21S 822. 83 A Neu5Ac2 6LacNAc trisaccharide equipped with a free thiol through a hydrophilic PEG3 spacer. The thiol reacts with maleimides to form stable thioether conjugates or with other thiols to form disulfide bonds; it is also compatible with thiol gold chemistry for surface immobilization. Neu5Ac2 6LacNAc is a ligand for Siglecs and for influenza hemagglutinin, particularly the human adapted strains that preferentially recognize 2 6