A short 5-Amino-1MQ half life means that a single daily dose might lead to significant peaks and troughs in plasma levels, which could impact the consistency of its biological effects
Such high GSSG concentrations are unlikely to occur in most subcellular compartments but could be reached in the secretory pathway or during titration experiments of transgenic cell lines with an upregulated GSSG transporter 35,63,64,77
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BPC-157 may also enhance the migration of tendon fibroblasts, as indicated by the transwell filter migration assay used in the study