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Once they are inside the mitochondrial matrix, LCFA-CoAs are readily oxidized and results in acetyl-CoA production

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In the future, the successful development of small molecule GLP-1 receptor agonists and therapy based on glucagon and other gut hormones may provide a broader arsenal for the treatment of both hyperglycaemia and overweight

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Beltsville, Maryland: US Department of Agriculture, Agricultural Service (2018)