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also stated that MTX-induced oxidative stress may cause glomerular and tubular damage by causing MTX accumulation in the kidney (Reference Li, Abe and Yamakawa42)

Nat Commun 16 , 7611 (2025)

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Of note, turnover in Keap1 was evident in control subjects but not patients and this may indicate greater Keap 1 activity in periodontitis neutrophils which in turn may afford greater inhibition on Nrf2

Further evidence indicates negative consequences for male descendants of fluoxetine-exposed (5-20 mg/kg) rats during the gestation and lactation periods

Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response