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A 6-week phase 1 study of participants without T2D who had overweight or obesity found reduced activation (estimated from blood oxygen level dependent signal functional MRI) in certain brain regions relevant to appetite regulation in response to high-fat/high-sugar food images among participants assigned to tirzepatide 10 mg as compared with placebo [75]

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Weight gained during treatment predicts 6-month body mass index in a large sample of patients with anorexia nervosa using ensemble machine learning

Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo