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In senescent cells, FOXO4 can help keep p53 in the cell nucleus, which supports senescent-cell survival
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Am J Physiol Endocrinol Metab (2013) 305(8):E94250.10.1152/ajpendo.00304.2013 259 ListEOBerrymanDEFunkKJaraAKelderBWangFet alLiver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles
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Converging data from several sources suggest, however, that IC/BPS can be conceptualized as a bladder pain disorder that is often associated with voiding symptomatology and other systemic chronic pain disorders
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