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For topical administration, a dose would be however much that minimally covers the target area

While some individuals may experience mild side effects like nausea, these typically subside over time as the body adjusts

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13 GABA in the gut-brain axis GABA as gut bacteria-derived metabolites is an amino acid derivative of glutamate, which is widely distributed in the mammalian CNS and significantly modulates synaptic suppression and effects on psychological diseases including behavioral disorders, insomnia, and pain