Rather than raising NAD+ systemically (as NMN or NR supplementation does), NNMT inhibition preserves NAD+ specifically in the tissue where metabolic dysfunction is most pronounced a precision approach that appeals to researchers studying tissue-specific metabolic regulation
Comment: A commenter stated that CPT code 78800 is assigned to APC 5591 in proposed Addendum B but is assigned to APC 5573 in the proposed Data Addendum B and 2 Times Rule files
while this update will increase the emphasis on Safety of Care, the other measure groups will remain integral in determining a hospital's ultimate rating
Pregnancy and Breastfeeding : Inform your provider if you are pregnant, planning to become pregnant, or breastfeeding
Note that these two documented starting doses are worlds apart in size 150 mcg versus 2.5 mg is a roughly 17-fold difference
HOPDs would have approximately 25 months from the publication of this final rule with comment period until the start of the mandatory reporting period in January 2028, and approximately 3.5 years from the publication of this final rule with comment period until the submission deadline for the CY 2028 data in May 2029, to implement any workflow modifications or organizational updates necessary to successfully report on the measure
