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Semaglutide may cause acute kidney injury or worsen chronic kidney disease, potentially requiring dialysis

Support for Long-Term Weight ManagementSemaglutide not only helps with weight loss but also supports maintaining a healthy weight over time of body weight

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An important mediator in the process of reduced feelings of hunger is the hormone leptin, which, in interaction with GLP-1, regulates satiety and controls reward and aversion, suppressing hunger by inhibiting the appetite inducers AgRP/NPY neurons, while stimulating the satiety inducers POMC neurons [17,118,119]

Beyond weight and glucose, they intersect with mental health : they can modulate mood and reward circuitry

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