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Iron overload promotes the polarization of M1 macrophages by increasing the levels of M1 markers interleukin-6, tumour necrosis factor, and interleukin-1 and decreasing the levels of M2 marker tissue transglutaminase-2 [81]

Measurement of specific antibody formation provides ancillary evidence of the response

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Pharmacol Rev 41:143210 Corpas FJ, Barroso JB, Carreras A, Valderrama R, Palma JM, Len AM, Sandalio LM, del Ro LA (2006) Constitutive arginine-dependent nitric oxide synthase activity in different organs of pea seedlings during plant development

Received: 22 June 2019 Accepted: 19 August 2019 Published: 28 November 2019 Glutathione (GSH), a compound derived of a combination of three amino acids - cysteine, glycine and glutamine - is the final product of homocysteine (Hcy) metabolism in the transsulfuration pathway

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