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If your genetic profile suggests lower GLP1R receptor responsiveness, a switch to tirzepatide or an adjusted protocol may yield better results than increasing your semaglutide dose

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10.1016/s0022-2143(97)90005-6 J

Emerging studies are exploring whether GLP-1s could also help slow the progression of kidney disease, though current findings are still preliminary

Feagan BG, Rutgeerts P, Sands BE, et al