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If you take your medication at night and then lie down immediately, this could worsen the burn

Samples that did not correctly inject, judged by lack of signal for the internal standard, on the MS were also omitted from analysis

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If this occurs: Allow additional time at room temperature (up to 30 minutes total) Very brief, gentle vortexing (35 seconds) as a last resort If aggregation persists, consider re-solubilizing in 10 mM HCl at a slightly lower concentration 6

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Collagen remodeling is a multi-week process governed by fibroblast gene expression, procollagen synthesis, and matrix metalloproteinase regulation