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doi: 10.1096/fba.2021-00022

"The role of glutathione in photosynthetic organisms: emerging functions for glutaredoxins and glutathionylation" (PDF)

[PubMed: 40204768] [Free PMC Article] Carvas AO, Leuthardt A, Kulka P, et al

Reduced, oxidized and protein-bound forms of homocysteine and other aminothiols in plasma comprise the redox thiol status A possible element of the extracellular antioxidant defense system

Many users in these forums attribute this reaction to acute mast cell activation triggered by the peptide complex, noting that they require the concurrent, daily use of potent systemic antihistamines (such as Xyzal) simply to tolerate the basic administration of the protocol