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Retrieved from Pillarisetti, L., & Agrawal, D

Nature 477 , 171178 (2011)

Patients with type 2 diabetes may require temporary bridging therapy with insulin or continued metformin to maintain glycaemic control during treatment interruption

Nevertheless, desacyl-ghrelin has been shown to regulate skeletal muscle metabolism, bone formation, and cardioprotection through mechanisms that appear to be independent of canonical GHSR signalling [253]