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PE134000: α-GalNAc-PEG3-Azide label-new O-glycosylation with Sialyl TF

SKU: 11900794609

4.4
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Description

O-glycosylation with Sialyl TF

11-Carboxy-3

α-D-GalNAc-Ser-NH-Biotin

Abnormal Akt signaling in bladder epithelial cell explants from patients with interstitial cystitis/bladder pain syndrome can be induced by antiproliferative factor treatment of normal bladder cells

enzymatic cleavage releases 4-nitrophenol

PE134000: α-GalNAc-PEG3-Azide label-new O-glycosylation with Sialyl TFC14H26N4O8 378. 38 An D N acetylgalactosamine (GalNAc) ligand equipped with an azide handle through a hydrophilic PEG3 spacer. The terminal azide couples to alkynes via copper catalyzed azide alkyne cycloaddition (CuAAC) or to DBCO and related strained alkynes via copper free click chemistry, forming stable 1,2,3 triazole linkages. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the

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