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As a result, laboratories can maintain confidence in the consistency of the materials they evaluate
Patients with certain health issues might need their doses adjusted to avoid problems
The MHRA advises that metformin commonly reduces B12 levels and recommends testing if deficiency is suspected (for example, in patients with anaemia or neuropathy) and considering periodic monitoring in people with risk factors such as higher doses, longer duration of treatment, or other risk factors for deficiency
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